Failure of selenium-ace to improve osteoarthritis
Affiliations:
Source: Br J Rheumatol. 1990 Jun;29(3):211-3
DOI: 10.1093/rheumatology/29.3.211
Publication date:
1990 Jun
E-Publication date:
Not specified
Availability: abstract
Copyright: © 1990 Oxford University Press
Language: English
Countries: Not specified
Location: Not specified
Correspondence address: Dr H. Bird : Clinical Pharmacology Unit (Rheumatism Research), Royal Bath Hospital Cornwall Road, Harrogate HG1 2PS, UK
Keywords
Article abstract
Selenium-ACE, a formulation containing the trace element selenium with three vitamins, is widely promoted for the treatment of arthritis. A controlled double-blind trial of Selenium-ACE in osteoarthritis failed to demonstrate any significant efficacy for the compound over placebo at 3 or 6 months though there was a non-significant trend to improvement in some clinical parameters in both groups. Side-effects were more frequently seen in the placebo group.