Effect of Dead-Sea brine and its main salts on cell growth in culture.
Affiliations:
Source: Pharmacology. 1987;35(6):339-47.
DOI: 10.1159/000138359
Publication date:
1987
E-Publication date:
May 6, 2008
Availability: abstract
Copyright: © 1987 S. Karger AG, Basel
Language: English
Countries: Not specified
Location: Not specified
Correspondence address: Jashovam Shani, Department of Pharmacology, Hebrew University School of Pharmacy, POBox 12065, Jerusalem 91120 (Israel)
Keywords
Article abstract
Diluted Dead-Sea brine and solutions of certain of its salts (chlorides and bromides of Na, K and Mg) were found to reversibly inhibit cell proliferation in culture. Bromides were more powerful as inhibitors than their chloride counterparts, and K salts were more effective than those of Na and Mg. KBr had the strongest inhibitory effect, which equalled that of diluted Dead-Sea brine at the same concentration. The favourable results of the Dead-Sea Spa treatment of psoriasis may thus be partly due to the penetration of minerals into the body, via the skin, with subsequent reinforcement of anti-proliferative mechanisms.