Aerobic fitness in patients with fibrositis. A controlled study of respiratory gas exchange and 133xenon clearance from exercising muscle

Authors: Bennett RM (1) , Clark SR (1) , Goldberg L (1) , Nelson D (1) , Bonafede RP (1) , Porter J (1) , Specht D (1)
(1) Oregon Health Sciences University
Source: Arthritis Rheum. 1989 Apr;32(4):454-60
DOI: 10.1002/anr.1780320415 Publication date: 1989 Apr E-Publication date: Dec. 9, 2005 Availability: abstract Copyright: © 1989 American College of Rheumatology
Language: English Countries: Not specified Location: Not specified Correspondence address: Not specified


Article abstract

Aerobic fitness was evaluated in 25 women with fibrositis, by having them exercise to volitional exhaustion on an electronically braked cycle ergometer. Compared with published standards, greater than 80% of the fibrositis patients were not physically fit, as assessed by maximal oxygen uptake. Compared with matched sedentary controls, fibrositis patients accurately perceived their level of exertion in relation to oxygen consumption and attained a similar level of lactic acidosis, as assessed by their respiratory quotient and ventilatory threshold. Exercising muscle blood flow was estimated by 133xenon clearance in a subgroup of 16 fibrositis patients and compared with that in 16 matched sedentary controls; the fibrositis patients exhibited reduced 133xenon clearance. These results indicate a need to include aerobic fitness as a matched variable in future controlled studies of fibrositis and suggest that the "detraining phenomenon" may be of relevance to the etiopathogenesis of the disease.

Find it online