Failure of selenium-ace to improve osteoarthritis

Authors: Hill J (1) , Bird HA (1)
(1) Clinical Pharmacology Unit (Rheumatism Research), Royal Bath Hospital
Source: Br J Rheumatol. 1990 Jun;29(3):211-3
DOI: 10.1093/rheumatology/29.3.211 Publication date: 1990 Jun E-Publication date: Not specified Availability: abstract Copyright: © 1990 Oxford University Press
Language: English Countries: Not specified Location: Not specified Correspondence address: Dr H. Bird : Clinical Pharmacology Unit (Rheumatism Research), Royal Bath Hospital Cornwall Road, Harrogate HG1 2PS, UK


Article abstract

Selenium-ACE, a formulation containing the trace element selenium with three vitamins, is widely promoted for the treatment of arthritis. A controlled double-blind trial of Selenium-ACE in osteoarthritis failed to demonstrate any significant efficacy for the compound over placebo at 3 or 6 months though there was a non-significant trend to improvement in some clinical parameters in both groups. Side-effects were more frequently seen in the placebo group.

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