Circulating opioid peptides during thermal stress.

Authors: Vescovi PP (1) , Gerra G (1) , Pioli G (1) , Pedrazzoni M (1) , Maninetti L (1) , Passeri M (1)
(1) Istituto di Clinica Medica Generale e Terapia Medica, University of Parma
Source: Horm Metab Res. 1990 Jan;22(1):44-6.
DOI: 10.1055/s-2007-1004846 Publication date: 1990 Jan E-Publication date: March 14, 2008 Availability: abstract Copyright: © Georg Thieme Verlag, Stuttgart · New York
Language: English Countries: Not specified Location: Not specified Correspondence address: Not specified


Article abstract

In the present study we have examined the response of endogenous opiates (beta-EP and Met-enk) and ACTH to a particular type of thermal stimulus such as sauna in 8 young healthy subjects. Sauna-induced hyperthermia resulted in an increase of plasma beta-EP and ACTH, but appeared to have no significant effect on circulating Met-enk. The different responses of ACTH, beta-EP and Met-enk to heat exposure indicate that hyperthermia represents a form of stress, which can trigger off a well-defined neuroendocrine reaction.

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