Comparative study of the influence of 3 types of mineral water in patients with idiopathic calcium lithiasis.

Authors: Caudarella R (1) , Rizzoli E , Buffa A , Bottura A , Stefoni S
(1) Dipartimento di Medicina Clinica e Biotecnologia Applicata D. Campanacci, Universit√° degli Studi
Source: J Urol. 1998 Mar;159(3):658-63.
DOI: 10.1016/S0022-5347(01)63695-4 Publication date: 1998 Mar E-Publication date: Not specified Availability: abstract Copyright: © 1998 American Urological Association, Inc. Published by Elsevier Inc. All rights reserved.
Language: English Countries: Not specified Location: Not specified Correspondence address: Not specified


Article abstract


While there is general agreement on the need to increase urinary volume in stone formers, contrasting opinions have been expressed about the hardness of water and stone incidence. We evaluate the influence of 3 types of mineral water on urinary analytes in 22 idiopathic calcium oxalate stone formers.


All patients underwent a nutritional and metabolic evaluation at baseline, and after a controlled diet including water with a high, medium or low calcium content.


In patients who drank water with high and medium calcium contents calcium excretion increased, although the results did not reach statistical significance. In those who drank water with the highest calcium content oxalate excretion significantly decreased (p = 0.05), as did the oxalate-to-calcium ratio (p = 0.05). Moreover, these modifications did not induce relevant changes in urinary saturation. In patients who drank water with the greatest amount of bicarbonate citrate excretion increased (p = 0.03).


Mineral water with a higher calcium content induced increased calcium excretion but significantly decreased oxalate excretion. These data are in accordance with those of others, who did not find definite evidence that hard water is more lithogenic than soft water. Furthermore, water components other than calcium can modify the tendency toward crystal formation, affecting inhibitory power and/or lithogenic salt excretion.

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