Spa adjuvant therapy improves diabetic lower extremity arterial disease.

Authors: Qiu Y (1) , Zhu Y (2) , Jia W (3) , Chen S (4) , Meng Q (5)
(1) Shandon Medical University (2) Tangshan Branch of Jinling General Hospital (3) Second Military Medical University (4) Southern Medical University (5) Nanjing Institute of Physical Education
Source: Complement Ther Med. 2014 Aug;22(4):655-61
DOI: 10.1016/j.ctim.2014.05.003 Publication date: 2014 Aug E-Publication date: May 12, 2014 Availability: abstract Copyright: © 2014 Elsevier Ltd. All rights reserved.
Language: English Countries: Not specified Location: Not specified Correspondence address: Zhu Y,
No. 5, Wenquan Road, Tangshan, Jiangning, 211131 Nanjing, China. Tel.: +86 025 80805491.
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Article abstract


To investigate the effect of spa adjuvant therapy on diabetic lower extremity arterial disease (LEAD).


128 patients with type II diabetes were separated into three groups according to the degree of lower extremity vascular stenosis. Patients within each group were then randomly divided to receive no treatment (control) or spa adjuvant therapy (treatment). Clinical symptoms, blood pressure and hemodynamic analyses were compared between control and treatment groups by Chi square or t-test.


After adjuvant therapy with spa, patients' pain, numbness, and cold sensation were significantly improved compared with control groups (P<0.05). Spa adjuvant therapy also significantly increased the dorsalis pedis pulse and systolic peak velocity ratio of patients with mild lower extremity vascular stenosis compared with control groups (P<0.05), while there were no significant differences between the two groups for patients with moderate and severe stenosis (P>0.05). Both in the spa and control groups, there were no significant differences before and after medication for fasting, 2-h postprandial blood glucose and glycosylated hemoglobin (HbA1C) analyses (P>0.05).


Spa adjuvant therapy can significantly alleviate lower extremity pain, numbness, and cold sensory symptoms in diabetic LEAD patients with stenosis. Moreover, in LEAD patients with mild stenosis, spa adjuvant therapy also improves the dorsalis pedis pulse and systolic peak velocity ratio, suggesting a potential role for spa therapy as an early intervention strategy to treat the initial stages of disease.

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