How double blind is double blind? And does it matter?
Affiliations:
(1) St Bartholomew's Hospital
Source: Br J Clin Pharmacol. 1976 Apr;3(2):331-2.
DOI: 10.1111/j.1365-2125.1976.tb00612.x
Publication date:
1976 Apr
E-Publication date:
July 4, 2012
Availability: full text
Copyright: © 1976 The British Pharmacological Society
Language: English
Countries: Not specified
Location: Not specified
Correspondence address: Not specified
Keywords
Article abstract
In an apparently double blind crossover study, two experienced measurement technicians were able to identify many of the treatment periods. They most often correctly identified aspirin, a drug with prominent effects and side effects. It is argued that in many circumstances it is better to use a blind observer who is not concerned with the giving of treatment or the collection of side effects.