Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis.
Affiliations:
(1) University Hospital Nijmegen
(2) University Hospital Groningen
Source: Arthritis Rheum. 1995 Jan;38(1):44-8
DOI: 10.1002/art.1780380107
Publication date:
1995 Jan
E-Publication date:
Dec. 9, 2005
Availability: abstract
Copyright: © 1995 American College of Rheumatology
Language: English
Countries: Not specified
Location: Not specified
Correspondence address: M. L. L. Prevoo,
Department of Rheumatology, University Hospital Nijmegen, P. O. Box 9101, 6500 HB Nijmegen, The Netherlands
Department of Rheumatology, University Hospital Nijmegen, P. O. Box 9101, 6500 HB Nijmegen, The Netherlands
Keywords
Article abstract
OBJECTIVE:
The development and validation of Modified Disease Activity Scores (DAS) that include different 28-joint counts.
METHODS:
These scores were developed by canonical discriminant analyses and validated for criterion, correlational, and construct validity. The influence of disease duration on the composition of the DAS was also investigated.
RESULTS:
No influence of disease duration was found. The Modified DAS that included 28-joint counts were able to discriminate between high and low disease activity (as indicated by clinical decisions of rheumatologists).
CONCLUSION:
The Modified DAS are as valid as disease activity scores that include more comprehensive joint counts.