Observation of the long-term effects of lifestyle intervention during balneotherapy in metabolic syndrome

Observation des effets à long terme d’une intervention comportementale réalisée au cours d’une cure thermale dans le syndrome métabolique
Authors: Gin H (1,2) , Demeaux JL (1) , Grelaud A (1,3) , Grolleau A (1,3) , Droz-Perroteau C (1,3,4) , Robinson P (1,3) , Lassalle R (1,3) , Abouelfath A (1,3) , Boisseau M (1) , Toussaint C (1) , Moore N (1,2,3,4)
(1) Université de Bordeaux (2) Centre Hospitalier Universitaire de Bordeaux (3) INSERM CIC-P 0005 (4) INSERM U657
Source: Therapie. 2013 May-Jun;68(3):163-7
DOI: 10.2515/therapie/2013025 Publication date: 2013 May E-Publication date: July 26, 2013 Availability: abstract Copyright: 2013 Société Française de Pharmacologie et de Thérapeutique.
Language: English, French Countries: France Location: Eugénie-les-Bains Correspondence address: Nicholas Moore, Université de Bordeaux, CHU de Bordeaux, INSERM U657, INSERM-CHU CIC 0005, Hôpital du Tondu, BP 41, 33076 Bordeaux, France. E-mail: nicholas.moore@pharmaco.u-bordeaux2.fr


Article abstract


Estimate the effect of lifestyle adjustment activities in patients with metabolic syndrome treated by prescribed balneotherapy.


Observational pilot cohort study with 12-month follow-up after multidimensional lifestyle training (physical, dietary, educational) during 3-week standard stay in the spa town of Eugénie-les-Bains.


Of 145 eligible patients, 97 were included; 63 were followed and analysable. At inclusion all had ≥3 National cholesterol education program-Adult treatment panel III (NCEP-ATPIII) criteria defining metabolic syndrome, 76.2% were female, mean age was 61.2 years. At the end of follow-up (median:10.4 months, Inter-Quartile Range: [6.7;11.4]), 48 of these 63 patients (76.2%) no longer had metabolic syndrome (95%CI [65.7;86.7]). These 48 patients without metabolic syndrome at the end of follow-up represented 49.5% of the 97 included (95%CI [39.5;59.4]).


Future studies of lifestyle interventions taking advantage of the spa environment can be expected to find least one third of patients free of metabolic syndrome at the end of 12-month follow-up in the intervention group.

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